Thomas O Metz Selected Research

Glucose (Dextrose)

3/2014	The succinated proteome.
7/2012	Discovery of novel glucose-regulated proteins in isolated human pancreatic islets using LC-MS/MS-based proteomics.
11/2009	Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets.
5/2008	Proteomic profiling of nonenzymatically glycated proteins in human plasma and erythrocyte membranes.
6/2007	Enrichment and analysis of nonenzymatically glycated peptides: boronate affinity chromatography coupled with electron-transfer dissociation mass spectrometry.
1/2007	Application of electron transfer dissociation mass spectrometry in analyses of non-enzymatically glycated peptides.
12/2006	Characterization of the human pancreatic islet proteome by two-dimensional LC/MS/MS.

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Thomas O Metz Research Topics

Disease

20	Infections 03/2023 - 01/2010
19	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 02/2024 - 02/2008
11	Diabetes Complications 03/2012 - 10/2003
10	Inflammation (Inflammations) 10/2022 - 06/2012
6	Chronic Disease (Chronic Diseases) 02/2024 - 02/2002
5	Virus Diseases (Viral Diseases) 01/2021 - 01/2012
5	Type 2 Diabetes Mellitus (MODY) 03/2016 - 12/2006
4	Neoplasms (Cancer) 01/2019 - 03/2014
3	COVID-19 03/2023 - 01/2022
3	Diabetes Mellitus 05/2008 - 01/2007
2	Kidney Diseases (Kidney Disease) 06/2023 - 01/2023
2	Rheumatoid Arthritis 06/2023 - 01/2023
2	Human Influenza (Influenza) 01/2017 - 05/2014
2	Wounds and Injuries (Trauma) 01/2017 - 08/2013
2	Hyperglycemia 08/2015 - 07/2011
2	Insulin Resistance 07/2012 - 11/2009
1	Metabolic Diseases (Metabolic Disease) 11/2023
1	Autoimmune Diseases (Autoimmune Disease) 07/2023
1	Crohn Disease (Crohn's Disease) 10/2022
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2022
1	Anorexia 01/2022
1	Nausea 01/2022
1	Body Weight (Weight, Body) 01/2021
1	Lung Diseases (Lung Disease) 01/2021
1	Vesicular Stomatitis 01/2021
1	Undiagnosed Diseases 01/2020
1	Zika Virus Infection 01/2020
1	Ebola Hemorrhagic Fever 12/2017
1	Sepsis (Septicemia) 12/2017
1	Pregnancy Complications 12/2017
1	Communicable Diseases (Infectious Diseases) 01/2017
1	Pain (Aches) 01/2017
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2017
1	Coinfection 01/2017
1	Bacterial Infections (Bacterial Infection) 05/2014
1	Mitochondrial Diseases (Mitochondrial Disease) 03/2014
1	Cysts 03/2014
1	Obesity 03/2014
1	Acute Lung Injury 08/2013
1	Retinoblastoma (Glioblastoma, Retinal) 07/2012

Drug/Important Bio-Agent (IBA)

25	Proteins (Proteins, Gene)FDA Link 11/2023 - 02/2002
15	LipidsIBA 01/2024 - 10/2003
14	Biomarkers (Surrogate Marker)IBA 11/2023 - 02/2008
7	Insulin (Novolin)FDA Link 02/2024 - 07/2012
7	Glucose (Dextrose)FDA LinkGeneric 03/2014 - 12/2006
5	Advanced Glycation End ProductsIBA 08/2015 - 02/2002
4	Complement System Proteins (Complement)IBA 02/2024 - 02/2023
4	CytokinesIBA 01/2020 - 06/2012
4	EnzymesIBA 12/2017 - 01/2010
4	Peptides (Polypeptides)IBA 07/2011 - 01/2007
3	Fatty Acids (Saturated Fatty Acids)IBA 07/2023 - 01/2010
3	SphingolipidsIBA 01/2020 - 01/2012
3	Glycated ProteinsIBA 02/2009 - 06/2007
2	Lysine (L-Lysine)FDA Link 06/2023 - 01/2023
2	AutoantibodiesIBA 01/2023 - 02/2008
2	Blood Proteins (Serum Proteins)IBA 01/2023 - 01/2013
2	xanthohumolIBA 10/2022 - 10/2020
2	InterferonsIBA 01/2020 - 09/2015
2	ProteomeIBA 08/2015 - 01/2013
2	PyridoxamineIBA 11/2003 - 10/2003
1	Growth Differentiation Factor 15IBA 11/2023
1	Cystine (L-Cystine)IBA 03/2023
1	FlavonoidsIBA 10/2022
1	SolutionsIBA 01/2022
1	Glycoproteins (Glycoprotein)IBA 01/2021
1	Bile Acids and Salts (Bile Acids)IBA 10/2020
1	CeramidesIBA 01/2020
1	Apoptosis Regulatory ProteinsIBA 01/2020
1	Interferon Type IIBA 01/2020
1	FructoseIBA 01/2018
1	AsparagineIBA 01/2018
1	SolventsIBA 01/2017
1	Biocompatible Materials (Biomaterials)IBA 01/2017
1	VaccinesIBA 01/2017
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2017
1	DisaccharidesIBA 12/2016
1	EstersIBA 09/2015
1	SilymarinIBA 08/2015
1	Blood Glucose (Blood Sugar)IBA 08/2015
1	Histones (Histone)IBA 05/2014
1	Dual Specificity Phosphatase 1IBA 05/2014
1	Type III Secretion SystemsIBA 05/2014
1	Fumarate Hydratase (Fumarase)IBA 03/2014
1	FumaratesIBA 03/2014
1	RNA (Ribonucleic Acid)IBA 01/2014
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 08/2013
1	Fibrinolysin FDA Link 08/2013
1	Karyopherins (Importin)IBA 04/2013
1	Transcription Factors (Transcription Factor)IBA 04/2013
1	Hormones (Hormone)IBA 04/2013
1	Antiviral Agents (Antivirals)IBA 04/2013
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2013
1	Plasminogen Activator Inhibitor 1IBA 07/2012
1	Nuclear RNAIBA 07/2012
1	Carrier Proteins (Binding Protein)IBA 07/2012
1	Messenger RNA (mRNA)IBA 07/2012
1	glucose-regulated proteinsIBA 07/2012

Therapy/Procedure

4	Therapeutics 07/2023 - 11/2003
1	Chronotherapy 01/2022
1	Precision Medicine 01/2019